Pipeline

Our Pipeline is comprised of Biologics, including the proprietary BEAT®MultispecificsTM platform, and one Cbl-b inhibitor small molecule, targeting the spectrum of immune cell engagement and indications across hematologic and solid tumors. If you are interested in exploring a partnership, Contact us.

Diversity of Immune Cell Engagement and Indications across Hematologic and Solid Tumors

Option for pipeline

ASSETS DESCRIPTION INDICATION
DISCOVERY PRECLINICAL PHASE 1 PHASE 2 PHASE 3
GLOBAL RIGHTS

(ABBV-2001)

CD38 x BCMA x CD3
Trispecific T-Cell Engager
Multiple Myeloma
ISB 880 (LAD191)
IL-1RAP antagonist mAb
Hidradenitis Suppurativa
Telazorlimab
(ISB 830)

ISB 830-X8
(STAR-0310)

OX40 antagonist mAb
Atopic Dermatitis
ISB 2301
IMMUNITE™ NK-Cell Engager
Solid Tumors
GRC 65327
Cbl-b Inhibitor
Solid Tumors

Current Design

ASSETS DESCRIPTION INDICATION
DISCOVERY PRECLINICAL PHASE 1 PHASE 2 PHASE 3
GLOBAL RIGHTS

(ABBV-2001)

CD38 x BCMA x CD3
Trispecific T-Cell Engager
Multiple Myeloma
ISB 880 (LAD191)
IL-1RAP antagonist mAb
Hidradenitis Suppurativa
Telazorlimab
(ISB 830)

ISB 830-X8
(STAR-0310)

OX40 antagonist mAb
Atopic Dermatitis
ISB 2301
IMMUNITE™ NK-Cell Engager
Solid Tumors
GRC 65327
Cbl-b Inhibitor
Solid Tumors
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Oncology

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Immunology

PRODUCTS

ASSETS

DESCRIPTION
CD38 x BCMA x CD3 TREAT™
Trispecific T-Cell Engager

INDICATION
Multiple Myeloma

PHASE

GLOBAL RIGHTS

PRODUCTS

ASSETS

ISB 880 (ALM27134)

DESCRIPTION
IL-1RAP antagonist mAb

INDICATION
Hidradenitis Suppurativa

PHASE

GLOBAL RIGHTS

PRODUCTS

ASSETS

Telazorlimab (ISB 830)

DESCRIPTION
OX40 antagonist mAb

INDICATION
Atopic Dermatitis

PHASE

GLOBAL RIGHTS

PRODUCTS

ASSETS

ISB 830-X8 (STAR-0310)

DESCRIPTION
OX40 antagonist mAb

INDICATION
Atopic Dermatitis

PHASE

GLOBAL RIGHTS

PRODUCTS

ASSETS

ISB 2301

DESCRIPTION
IMMUNITE™ NK-Cell Engager

INDICATION
Solid Tumors

PHASE

GLOBAL RIGHTS

PRODUCTS

ASSETS

GRC 65327

DESCRIPTION
Cbl-b Inhibitor

INDICATION
Solid Tumors

PHASE

GLOBAL RIGHTS